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Peptide Planning App

Company: PSU Medina Lab 1

Major(s):
Primary: BME
Secondary: CMPSC

Non-Disclosure Agreement: NO

Intellectual Property: NO

The Medina lab interfaces chemical biology and peptide design to create new diagnostic and therapeutic biotechnologies in precision medicine. This work often requires members of the lab to chemically synthesize and characterize peptide reagents. While the chemical synthesis part of this work has been optimized, the steepest learning curve for many of the lab personnel is understanding how to characterize and further modify the peptides synthesized. The primary goal of this project is to create software/app that can allow users to input amino acid sequences and output predicted biophysical and analytical properties, including: molecular weight, predicted secondary structure, predicted solubility and mass spectrometry peaks. Secondary goals include an add on functionality that allow users to calculate the amount of reagents needed for secondary chemical functionalization of fabricated peptides. The software/app should be simple and easy for users to navigate and use with little or no coding experience.

 
 

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Our mission is to help bring the real-world into the classroom by providing engineering students with practical hands-on experience through industry-sponsored and client-based capstone design projects. Since its inception, the Learning Factory has completed more than 1,800 projects for more than 500 different sponsors, and nearly 9,000 engineering students at Penn State University Park participated in such a project.

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The Pennsylvania State University

University Park, PA 16802