Project Details

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Uncovering the Role of Human Milk Peptides

Company: PSU Medina Lab 2

Major(s):
Primary: BME
Secondary: CMPSC

Non-Disclosure Agreement: NO

Intellectual Property: YES

Human milk is composed of an array of biomolecules that are finely tuned to support the health of mother and baby. While much is known about the role fats and carbohydrates play in human milk, little is known about the function of milk peptides. These peptides arise from digestion of milk proteins in the infant gastric fluid. This project will utilize a suite of computational tools to generate hypotheses on the functional role these peptides play in human physiology. These tools will include use of online protease prediction algorithms to predict protein degradation sites, Alphafold software to determine structure of the resultant peptides, and co-factor tolls (e.g., AlphaFill) to predict peptide function.